eBook, ePUB

Electroporation-Based Therapies for Cancer (eBook, ePUB)

From Basics to Clinical Applications

Redaktion: Sundararajan, Raji

Beschreibung

Electroporation-Based Therapies for Cancer reviews electroporation-based clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-mediated, enhanced drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these patients for palliative and other care with enhanced quality of life. This book features discussions by interdisciplinary authors-including practicing oncological surgeons, medical professionals, and academic and other researchers-of the basics and clinical medical applications of electroporation. - Provides novel and recent clinical applications of electrochemotherapy for various cancers, including melanomas, sarcomas, superficial extreme melanoma, chest wall breast carcinoma, and colorectal cancers - Extensive study of a number of cell lines, including human breast cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irreversible electroporation techniques - In vitro study of delivery of various commonly prescribed/administered breast cancer chemo and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen

Technische Details

• Geräte: eReader
• ohne Kopierschutz

Barrierefreiheit

• Text-to-Speech
• Keine oder unzureichende Informationen zur Barrierefreiheit

Autor

Dr Raji Sundararajan is an Associate Professor at the Electrical and Computer Engineering Technology Department, Purdue University, since fall 2006. She obtained her initial training on electroporation at Johns Hopkins Medical School and has been doing research on electroporation for the past several years. She has authored/co-authored over 130 publications and has won several research and teaching awards and honors. She was the recipient of the 2010 Indiana 'Women & Hi-Tech' award for 'Distinguished use of technology in healthcare Life Science' and won prestigious, one year (2010-11) fellowship to study regenerative medicine therapy using optoinjection and electroporation techniques at Purdue. She is a reviewer of NIH, NSF, US International Science & Technology Center, and US National Research Council proposals and various journals including International Journal of Cancer, Molecular Biotechnology, Journal of Biomedical Microdevices, Journal of Anticancer drugs, a number of IEEE

Transactions and Journal of Electrostatics, etc. She is continually invited for keynote, workshop, panel moderator, invited talks, etc. for many conferences. Dr. Sundararajan, an IEEE Senior Member, is very active in various IEEE societies, including serving as Associate Editor of an IEEE Transactions and chairing two IEEE Standards task forces. A fellow of Institution of Engineers, India, Dr. Sundararajan is also the Conference Chair for IEEE International Conference on Electrical Insulation and Dielectric Phenomena (CEIDP - 2010 and 2011) and the President of Electrostatics Society of America (ESA-2009, 10, and 11) both with sessions on biomedical applications of electrical phenomena.

Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 352
• Erscheinungstermin: 28. August 2014
• Englisch
• ISBN-13: 9781908818294
• Artikelnr.: 41823464

Rezensionen

"...Key features include: Novel and recent clinical applications of electrochemotherapy for various cancers; An extensive study of a number of cell lines,.using both reversible and irreversible electroporation techniques..." --Anticancer Research