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Continuous Granulation with a Twin-Screw Extruder (eBook, PDF)

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Continuous granulation with a twin-screw extruder Dr. Dejan Djuric The feasibility of a twin-screw extruder for a continuous wet granulation process was investigated. On the one hand the impact of different screw configurations and process parameters on granule and tablet properties was evaluated. On the other hand mixing properties of several screw configurations were tested with respect to a continuous process including mixing and granulation in one process step. Furthermore a comparison of differently sized twin-screw extruders was performed to evaluate differences and simil...

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