Beta-Arrestins (eBook, PDF)
eBook, PDF

Beta-Arrestins (eBook, PDF)

Methods and Protocols

Redaktion: Scott, Mark G. H.; Laporte, Stéphane A.
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This volume looks at various approaches to study the pleiotropic roles of b-arrestins (b-arrs) in the control of signal transduction, and the resulting cellular and in vivo consequences that arise. The chapters in this book cover diverse topics around b-arrs such as their established roles in GPCR regulation and trafficking; regulatory scaffolding functions of b-arrs in MAPK signaling, cAMP hydrolysis and cytoskeletal dynamics; proteomic analysis of the b-arr interactome; mathematical modelling of b-arr signaling networks; functional selectivity involving biased ligands; nucleocytoplasmic traf...

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