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Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors (eBook, ePUB)

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Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson's disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson's disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use. - Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors - Preclinical models in COMT inhibitor devlopment - Transgenic COMT mice - latest information summarized - Chemistry of COMT inhibitors and their design with...

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