UV AND HPLC Method Development and Method Validation of Nevirapine
Tirthankar Choudhury
Broschiertes Buch

UV AND HPLC Method Development and Method Validation of Nevirapine

UV AND HPLC Method Development and Validation of Nevirapine in Bulk and Pharmaceutical dosage forms

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This research work focused on UV and RP-HPLC method and method validation of Nevirapine accurately and economically. UV spectrophotometric method and mehod development for Nevirapine obeyed Beer's law as depicted by linearity of the developed method. A reverse phase HPLC (RP-HPLC) method is described for the determination of nevirapine in tablet dosage forms. Chromatography was carried on an ODS column using a mixture of methanol and water (89:11 v/v) as the mobile phase at a flow rate of 1 mL/min with detection at 284 nm. The method was validated by determining its sensitivity, accuracy and p...