Understanding Extended Spectrum Beta-Lactamase(ESBL)Among Pseudomonas

Understanding Extended Spectrum Beta-Lactamase(ESBL)Among Pseudomonas

A Rational Way To Prescribe Antibiotic before treatment

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Being Gram-negative bacteria, most Pseudomonas spp. are naturally resistant to penicillin and the majority of related beta-lactam antibiotics, but a number are sensitive to piperacillin, imipenem, ticarcillin, or ciprofloxacin. Aminoglycosides such as tobramycin, gentamicin, and amikacin are other choices for therapy.This ability to thrive in harsh conditions is a result of their hardy cell walls that contain porins. Pseudomonas aeruginosa is increasingly recognized as an emerging opportunistic pathogen of clinical relevance. One of its most worrying characteristics is its low antibiotic susce...