UBQLN2
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Ubiquilin-2 is a protein that in humans is encoded by the UBQLN2 gene. This gene encodes a ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to aff...
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Ubiquilin-2 is a protein that in humans is encoded by the UBQLN2 gene. This gene encodes a ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.
