Twenty Years of G-CSF
Broschiertes Buch

Twenty Years of G-CSF

Clinical and Nonclinical Discoveries

Herausgegeben: Molineux, Graham; Foote, MaryAnn; Arvedson, Tara
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Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting.This Milestones in Drug Therapy volume describes the experience of the last 20 ye...