Tumor Necrosis Factors
Versandkostenfrei!
Versandfertig in 6-10 Tagen
22,99 €
inkl. MwSt.
PAYBACK Punkte
11 °P sammeln!
High Quality Content by WIKIPEDIA articles! Tumor necrosis factors (or the TNF-family) refers to a group of cytokines family that can cause cell death. At the end of 19th century William Coley, a New York surgeon, described remission of tumors following bacterial infection. In 1975 a protein responsible for this process was identified and called tumor necrosis factor alpha (TNF-alpha). An article on the history of fever therapy, as it was called, and TNF up to 1991, with references to clinical and double-blind studies but under the heading of complementary and alternative therapies, has been p...
High Quality Content by WIKIPEDIA articles! Tumor necrosis factors (or the TNF-family) refers to a group of cytokines family that can cause cell death. At the end of 19th century William Coley, a New York surgeon, described remission of tumors following bacterial infection. In 1975 a protein responsible for this process was identified and called tumor necrosis factor alpha (TNF-alpha). An article on the history of fever therapy, as it was called, and TNF up to 1991, with references to clinical and double-blind studies but under the heading of complementary and alternative therapies, has been published. TNF acts via the TNF Receptor (TNF-R) and is part of the extrinsic pathway for triggering apoptosis. TNF-R is associated with procaspases through adapter proteins (FADD, TRADD, etc.) that can cleave other inactive procaspases and trigger the caspase cascade, irreversibly committing the cell to apoptosis.
Andere Kunden interessierten sich für
