TREATMENT OF LATE-ONSET SYNDROMES SECONDARY TO NEUROLEPTICS

TREATMENT OF LATE-ONSET SYNDROMES SECONDARY TO NEUROLEPTICS

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Remission rates for late onset syndromes, a serious and disabling side effect of dopamine receptor blocking agents, are low overall. An accurate phenomenological classification of these syndromes is needed to tailor treatment. The recommended treatment options have a low level of evidence. Clozapine has proven to be effective in clinical practice, particularly in cases of resistant schizophrenia and late onset syndrome. Other therapeutic alternatives seem promising.