The Variation and Adaptive Expression of Antibodies
George P. Smith
Gebundenes Buch

The Variation and Adaptive Expression of Antibodies

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During the past ten years, several theories have been proposed on the origin of the diversity of antibodies. George P. Smith presents a critical study of these theories in this detailed treatment of immunological problems from the point of view of molecular genetics.Mr. Smith uses a new and simplifying approach to this long-standing controversy. By a comprehensive computerized analysis of antibody amino acid sequences (particularly the myeloma proteins), the author traces their evolution and matches his results against the expectations of the various theories of diversity. He discusses at leng...