The Synthesis of an Internal Standard for Bicalutamide

The Synthesis of an Internal Standard for Bicalutamide

Versandkostenfrei!
Versandfertig in 6-10 Tagen
36,99 €
inkl. MwSt.
PAYBACK Punkte
18 °P sammeln!
(R,S)-Bicalutamide [N-(4-cyano-3-trifluoromethylphenyl)- -methyl- -hydroxy-beta-(4- fluorophenylsulfonyl)propanamide], sold as Casodex®, is the leading antiandrogen currently used to treat prostate cancer. It binds to androgen receptors and blocks cancer growth. This work aims to develop internal standards for the bio-analytical component of clinical trials that are required to detect bicalutamide and derivatives. An internal standard is added to the body fluid sample (mostly blood) at the beginning of the sample work up at about the same concentration of the analyte to be quantified. An idea...