The Pacemaker Channels of the Heart: From Reductionism to Systems Biology
Denis Noble
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The Pacemaker Channels of the Heart: From Reductionism to Systems Biology

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In The Pacemaker Channels of the Heart, Denis Noble chronicles the fascinating journey of his research into one of biology's most essential functions - the rhythmic beating of the heart. Written by the founder of mathematical heart modelling, this book traces scientific developments spanning over sixty-five years, from the pioneering 1960 heart rhythm model to the sophisticated integrative models of today. This journey follows the evolution of cardiac electrophysiology through the discovery of potassium and slow channels, analytical modelling, and the development of the electrocardiogram. Beyo...