Broschiertes Buch

The Giant Vesicle Book

Beschreibung

Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts.

Key Features

- A complete summary of the field, covering fundamental concepts, practicalmethods, core theory, and the most promising applications

- A start-up package of theoretical and experimental information for newcomers in the field

- Extensive protocols for establishing the required preparations and assays

- Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls

- Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques

- Handy tables with data and structures for ready reference

Autor

Rumiana Dimova leads an experimental lab in biophysics at the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany. She has been working with giant vesicles already from the beginning of her scientific career. After being introduced into the magic of their preparation during her studies as a student in Bulgaria, she remained fascinated by their application and over the years pursued a variety of projects employing giant vesicles as a platform to develop new methods for the biophysical characterization of membranes and processes involving them. Until now, these studies have resulted in more than hundred peer-reviewed publications. Recently, she was also awarded the Emmy Noether distinction for women in physics of the European Physical Society. Carlos Marques, a CNRS senior scientist, founded the MCube group at the Charles Sadron Institute in Strasbourg, France, where he gears experimental and theoretical research towards the understanding of the physical properties of self-assembled lipid bilayers. Trained as a polymer theoretician, Carlos first got interested in membranes because they interact with polymers and published the first prediction for the membrane changes expected when polymers adsorb on lipid bilayers. He then expanded the scope of his group to include experiments and numerical simulations, and has now published many papers based on research with giant unilamellar vesicles, including the first study of lipid oxidation in GUVs and the discovery of the so-called PVA method for vesicle growth.

Produktdetails

• Verlag: CRC Press / Taylor & Francis
• Seitenzahl: 676
• Erscheinungstermin: 14. Juni 2022
• Englisch
• Abmessung: 277mm x 218mm x 30mm
• Gewicht: 2060g
• ISBN-13: 9781032337890
• ISBN-10: 1032337893
• Artikelnr.: 64268056

Rezensionen

"Giant vesicles are artificial membrane systems used in basic biological research, applied research on smart materials, and medical and pharmaceutical applications. This massive volume provides a collection of 30 review articles, each an independent chapter, on this important topic. Editors Dimova (Max Planck Institute) and Marques (French National Centre for Scientific Research) are experts in the field, and the contributors represent an international group, with the majority of authors hailing from European countries. The chapters cover a diverse array of topics, including biophysics, cell and molecular biology, and physical chemistry. Because biophysics is a consideration, many chapters feature detailed mathematical treatments. The early part of the book provides a good summary of the field and its fundamental concepts. The articles are well referenced, drawing from the primary literature, and most include citations up to 2018. The book is beautifully illustrated with nice figures and callout boxes that highlight important protocols-some parts of the book resemble an advanced textbook. Chapter 4 (on the cytoskeleton) and chapter 10 (on light microscopy) were particularly informative to this reviewer. Chapters 15 and 19 provide web links to videos illustrating important concepts in vesicle dynamics. Several appendixes on topics such as membrane dyes and detergents are included."
-J. Z. Kiss, UNC-Greensboro, in CHOICE November 2020