The genome stability is preserved by a stress response protein: CCDC6

The genome stability is preserved by a stress response protein: CCDC6

CCDC6 negatively modulates the phosphatase activity PP4c in DNA Damage Response, maintaining the genome stability

Versandkostenfrei!
Versandfertig in 6-10 Tagen
32,99 €
inkl. MwSt.
PAYBACK Punkte
16 °P sammeln!
The maintenance of genomic stability is beneficial for the survival of an individual cell and crucial for cancer avoidance. Cells invest huge resources to maintain genomic stability, and cancer cells undergo an array of genetic changes to escape these barriers. The initiation of carcinogenesis represents a mutational event, which in most instances occurs despite functional DNA damage response (DDR) mechanisms. This dissertation aims to study the mechanisms of chromosomal instability in tumor development. We intend to investigate the role of CCDC6, a gene frequently rearranged with RET and with...