Michael L. Gross / Richard M. Caprioli (eds.)

Gebundenes Buch

The Encyclopedia of Mass Spectrometry

Volume 6: Ionization Methods

Beschreibung

Main description:
Volume 6 of the Encyclopedia of Mass Spectrometry serves as a concise review of the current ionization methods used in mass spectrometry today. The majority of chapters include tutorials describing the principles and instrumentation applied to each method. Techniques covered include ionization of gas-phase molecules by particles and photons, ionization of ion-molecule and molecule-molecule reactions, ionization in strong electric fields, spray methods for ionization, desorption ionization by particle bombardment and biophysical applications of desorption and spray ionization. The selection of appropriate methods of ionization for analysis of various substances is also considered.

- reviews range of ionization methods used in mass spectrometry today
- includes tutorials describing the principles and instrumentation applied to each method
- considers appropriate methods of ionization for analysis of various substances

Table of contents:
1. Fundamentals of Ionization
2. General Considerations for Ionization
3. Ionization of Gas-Phase Molecules by Particles and at High Temperature: Electron Ionization (EI), Positron Ionization, and Surface Ionization Organic MS
4. Ionization of Gas-Phase Molecules by Photons: Photoionization (PI), Photoelectron Spectroscoy (PES) and Laser Ionization
5. Ionization by Ion-Molecule and Molecule-Molecule Reactions: Chemical Ionization (CI), Atmospheric Pressure Chemical Ionization (APCI), and DART
6. Ionization in Strong Electric Field
7. Spray Methods for Ionization
8. Desorption Ionization by Particle Bombardment: SIMS, Fast Atom Bombardment, and High-Energy Bems
9. Desorption by Photons: Laser Desorption and Matridx-Assisted Laser Desorption Ionization (MALDI)
10. Biophysical Application of Desorption and Spray Ionization
11. Choice of Ionization for Analysis of Various Substances

Autor

Michael L. Gross is Professor of Chemistry and Professor of Medicine at Washington University, St. Louis, as well as Director of the NIH Mass Spectrometry Research Resource located at Washington University.
Background,
1966: Ph.D., University of Minnesota
1987: Commonwealth of Massachusetts Pioneer Award, "In Search of the Health Consequences of Dioxin in Our Environment"
1983 -1991: Identified as one of the 50 most cited chemists
1999: Field and Franklin Award of The American Chemical Society
2001: Outstanding Graduate Student Mentor, Washington University
Biography Richard M. Caprioli is the Stanley Cohen Professor of Biochemistry and Director of the Mass Spectrometry Research Center at Vanderbilt University School of Medicine. He is also currently Professor in the Departments of Chemistry and Pharmacology at Vanderbilt.

Produktdetails

• Verlag: Elsevier Science
• Englisch
• ISBN-13: 9780080438016
• ISBN-10: 0080438016
• Artikelnr.: 21911274