Teratogenicity of Mucophylline on Albino rats

Teratogenicity of Mucophylline on Albino rats

Teratogenic effects of Bronchodilators drug on the pregnant female of Albino rats and their offsprings

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The present book aimed to evaluate the teratogenic effects of the Mucophylline is daily oral administered to the pregnant albino rats. The pregnant animals treated during the gestational period (5th - 19th day of gestation) with doses 30.83 mg/Kg and 66.61 mg/Kg. On the 20th day of gestation, the animals were sacrificed and the numbers of implanation sites, resorbed and live fetuses were counted. The placental weight, fetal weight, length and tail length were recorded. The external morphology and skeletal malformations, histological studies of maternal and fetal tissues were evaluated. Also th...