Synthetic and Biophysical Studies on the Tridachiahydropyrone Family of Natural Products
Kimberley Jade Powell
Gebundenes Buch

Synthetic and Biophysical Studies on the Tridachiahydropyrone Family of Natural Products

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This thesis addresses fundamental scientific questions such as:How are complex natural products synthesized in vivo?Can we replicate these conditions in a laboratory environment?What is the biological function of such secondary metabolites?What are the biological origins of chirality?These issues are explored in an accessible manner using a multidisciplinary approach spanning chemistry, biology and physics to investigate an interesting family of complex natural products isolated from marine molluscs - the tridachiahydropyrones.The work has achieved:Elegant biomimetic syntheses of a number of t...