Cornelia Locher

Broschiertes Buch

Synthesis of Tetrahydroisoquinolines

A Benzotriazole-Mediated Approach

Beschreibung

Using benzotriazole as auxiliary gives convenient access to a range of 1,2,3,4-tetrahydroisoquinolines with different aromatic substitution patterns. In the light of the well-known difficulties in the preparation of derivatives with electron-withdrawing aromatic substituents and the interesting pharmacological properties of these compounds, the simple procedures and conditions of the described reactions as well as the very high yields, which are frequently obtained, make this approach an important new route to the 1,2,3,4-tetrahydroisoquinoline skeleton.

Autor

Dr Cornelia Locher is a Senior Lecturer at the School of Pharmacy and Curtin Health Innovation Research Institute (CHIRI), Curtin University of Technology, Perth, Australia.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 308
• Erscheinungstermin: 21. Mai 2010
• Englisch
• Abmessung: 220mm x 150mm x 20mm
• Gewicht: 477g
• ISBN-13: 9783838310343
• ISBN-10: 3838310349
• Artikelnr.: 27074996