
Synthesis of quinolinyl ureas via Pd catalyzed C- N coupling
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An efficient catalytic system for the synthesis of quinolinyl ureas have been developed using Pd based catalyst system. All these synthesized quinolinyl ureas have adequate pledge as active drug candidates via a novel process. The in vitro biological screening data of the newly synthesized analogs revealed that majority of the compounds have demonstrated noticeable antimicrobial against various panels of microorganisms.