Synthesis & Biological Evaluation of Metal Complexes With Beta-Lactam

Synthesis & Biological Evaluation of Metal Complexes With Beta-Lactam

An analytical approach

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Beta lactam derivatives exhibit a range of bioactivities, including anti-angiogenic, anti-tumour, anti-malarial, anti-inflammatory and analgesic, anti-tubercular, anti-glaucoma, anti-HIV, cytotoxic and antimicrobial properties. The synthesis of metal complexes of lactam derivatives had received much attention due to the fact that they are among the first effective chemotherapeutic agents to be employed for the prevention and cure of bacterial infection in humans. The pharmacological activity of these types of molecules is often enhanced by complexation with metal ions.Certain theories had been...