Surface modification of superparamagnetic iron oxide nanoparticles
Esther Amstad
Broschiertes Buch

Surface modification of superparamagnetic iron oxide nanoparticles

Surface functionalizing superparamagnetic iron oxide nanoparticles using nitrocatechol anchors

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Biomedical applications of superparamagnetic iron oxide nanoparticles (NPs) for therapeutic and diagnostic purposes require NPs to be stable under physiologic conditions. This can only be achieved if NPs are sterically stabilized with appropriate dispersants that bind irreversibly to the iron oxide surface. Tight control over the dispersant layer not only prevents NP agglomeration but additionally paves the way to tailor NP size, charge, the type and density of functionalities presented at the NP surface. These factors are especially important for the in vivo performance of NPs. One possibilit...