Superconducting strip-lines for mass spectrometry
Alessandro Casaburi
Broschiertes Buch

Superconducting strip-lines for mass spectrometry

Development and Characterization of innovative SC detectors for unprecedented performances in time-of-flight mass spectrometry

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The emerging life sciences (genomics, proteomics...) require to the modern time-of-flight mass spectrometry (TOF-MS) the capability to identify and quantify massive macromolecules with masses larger than 100 kDa. The detectors commonly used in TOF-MS have both sensitive area of square centimeters for a good geometric efficiency and a sub-nanosecond response time for a small mass resolution. Anyway they suffer a serious loss in detection efficiency for masses above 4 kDa up to become completely insensitive for values of about 100 kDa, limiting the effectiveness of the TOF-MS technique. Here, I ...