Study of molecular interactions in drug mixtures
Farida AllalManel SELLALI
Broschiertes Buch

Study of molecular interactions in drug mixtures

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Molecular drug/coformer interactions were deduced from thermodynamic and thermophysical properties. Measurements of the liquid-solid equilibrium diagrams of two binary systems M.HCl + L-Proline and or + L-Arginine revealed single and double eutectic systems respectively. The diagram for the M.HCl + L-Arginine binary system also shows a defined compound. This corresponds to a P.A/Coformer cocrystallization facilitated by the existence of several functional groups. XRD, SEM and IR analysis confirmed the existence of a new compound with chemical formula C10H26N9ClO2The densities of the ternary sy...