Structure and Dynamics of Non-Native States of Proteins
Satish Kumar
Broschiertes Buch

Structure and Dynamics of Non-Native States of Proteins

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Protein aggregation and deposition in different tissues culminates in a wide range of diseases like Alzheimer's, Parkinson's. Aggregated proteins poses challenges to pharmaceutical industries also, where formation of inclusion bodies reduces the yield and shelf-life of recombinant proteins. Thus understanding the mechanism of protein aggregation and inhibition is urgently required to delineate the pathogenicity linked with several diseases and to circumvent the problems associated with the isolation and long term storage of biopharmaceutical protein drugs. Here, we proposed the aggregation mec...