Structural Approaches to Sequence Evolution
Broschiertes Buch

Structural Approaches to Sequence Evolution

Molecules, Networks, Populations

Herausgegeben: Bastolla, Ugo; Porto, Markus; Roman, Eduardo; Vendruscolo, Michele
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Structural requirements constrain the evolution of biological entities at all levels, from macromolecules to their networks, right up to populations of biological organisms. Classical models of molecular evolution, however, are focused at the level of the symbols - the biological sequence - rather than that of their resulting structure. Now recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements in...