Gebundenes Buch

Stem Cell Biology in Neoplasms of the Central Nervous System

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This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used.The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neop...