Statistical Modeling for the Analysis of MALDI-TOF Mass Spectrometry
Qi Zhu
Broschiertes Buch

Statistical Modeling for the Analysis of MALDI-TOF Mass Spectrometry

Approaches dealing with Labeled and Label-free Peptide Applications

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The analsyses involve novel as well as application oritented statistical methodologies applied to the mass spectrometry based proteomics data. This is a new research area in the statistical point of view, and it requires non-routine statistical modeling approaches. The analyses are based on the assumption of unknown peptide sequences. In such situation, more elaborate statistical modeling approaches need to be developed, to account for the uncertainty caused by the estimation of the masses of the peptides. Two topics are considered in the analyses. The first topic is to separate and quantify o...