Stability Indicating Assay Method For Bisacodyl as Per ICH Guidelines

Stability Indicating Assay Method For Bisacodyl as Per ICH Guidelines

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In this study, it is possible to develop to selective and validated stability-indicating HPLC assay method for bisacodyl on a C18 column, which could separate the drug and its degradation products formed under a variety of stress conditions. Bisacodyl was found to be less stable in solution state, whereas it was comparatively much stable in solid state. The method proved to be simple, accurate, precise, specific and selective. Hence it is recommended for analysis of the drug and degradation products in stability samples by the industry.Indirectly, the study highlights the benefit of the use of...