Spike-Triggered Covariance
Electrophysiology
Herausgegeben: Sundara, Oscar
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Spike-triggered covariance (STC) analysis is a tool for characterizing a neuron's response properties using the covariance of stimuli that elicit spikes from a neuron. STC is related to the spike-triggered average (STA), and provides a complementary tool for estimating linear filters in a linear-nonlinear-Poisson (LNP) cascade model. Unlike STA, the STC can be used to identify a multi-dimensional feature space in which a neuron computes its response. STC analysis identifies the stimulus features affecting a neuron's response via an eigenvector decomposition of the spike-triggered covariance ma...
Spike-triggered covariance (STC) analysis is a tool for characterizing a neuron's response properties using the covariance of stimuli that elicit spikes from a neuron. STC is related to the spike-triggered average (STA), and provides a complementary tool for estimating linear filters in a linear-nonlinear-Poisson (LNP) cascade model. Unlike STA, the STC can be used to identify a multi-dimensional feature space in which a neuron computes its response. STC analysis identifies the stimulus features affecting a neuron's response via an eigenvector decomposition of the spike-triggered covariance matrix. Eigenvectors with eigenvalues significantly larger or smaller than the eigenvalues of the raw stimulus covariance correspond to stimulus axes along which the neural response is enhanced or suppressed.
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