Specific components of aversive odor memory in Drosophila melanogaster
Stephan Knapek
Broschiertes Buch

Specific components of aversive odor memory in Drosophila melanogaster

Synapsin and Bruchpilot, two presynaptic proteins underlying specific phases of olfactory aversive memory in the fruit fly

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Memory is dynamic: after pairing an odor with electric shocks, flies form an aversive odor memory that lasts for several hours and consists of qualitatively different components. An anesthesia-sensitive memory component (ASM) decays rapidly, whereas a consolidated anesthesia-resistant memory component (ARM) lasts significantly longer. Here the author shows that the evolutionary conserved phosphoprotein Synapsin is selectively required for the labile ASM. Synapsin is associated with a reserve pool of vesicles at the presynapse and is required to maintain vesicle release specifically under susta...