Broschiertes Buch

Sodium Thiopental

Beschreibung

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Barbiturates are a class of drugs that act on the GABAA receptor in the brain and spinal cord. The GABAA receptor is an inhibitory channel that decreases neuronal activity, and barbiturates enhance the inhibitory action of the GABAA receptor. Barbiturates, benzodiazepines, and alcohol all bind to the GABAA receptor. Barbiturates that act on the barbiturate binding site of the GABAA receptor directly gate the chloride ion channel of the GABAA receptor, whereas benzodiazepines acting on the benzodiazepine site on the GABAA receptor increase the opening frequency of the chloride ion channel. This explains why overdoses of barbiturates may be lethal whereas overdoses of benzodiazepines alone are typically not lethal. Another explanation is that barbiturates can activate GABA receptors in the absence of the GABA molecule, whereas benzodiazepines need GABA to be present to have an effect: this may explain the more widespread effects of barbiturates in the central nervous system. Barbiturates have anesthetic, sedative, anxiolytic, anticonvulsant and hypnotic properties. Benzodiazepines do not have analgesic effects.

Produktdetails

• Verlag: Betascript Publishing
• Seitenzahl: 76
• Englisch
• Abmessung: 220mm
• Gewicht: 119g
• ISBN-13: 9786131019951
• ISBN-10: 6131019959
• Artikelnr.: 29876288