Self Microemulsifying Drug Delivery System For Some Drugs
Vikrant Wankhade
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Self Microemulsifying Drug Delivery System For Some Drugs

Development And Evaluation Of Self Microemulsifying Drug Delivery System For High Molecular Weight Drugs

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BCS class II are poorly water soluble and some drugs have high molecular weight, more than eleven hydrogen bond acceptors, more than five hydrogen bond doner. Thus, it exhibits poor bioavailability. A new Solid-Self Emulsifying Drug Delivery System (S-SMEDDS) of Drugs has been successfully developed to enhance its oral bioavailability by improving its solubility and facilitating high molecular weight of Drugs absorption. The primary composition of SMEDDS formulation was selected from solubility, pseudoternary phase diagram, emulsifying efficiency and compatibility test for preparation of (L-SM...