Self Micro Emulsifying Drug Delivery System of Ramipril
Miss Jill Shukla
Broschiertes Buch

Self Micro Emulsifying Drug Delivery System of Ramipril

Formulation and Evaluation of Oral Self Microemulsifying Drug Delivery System of Ramipril

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Oral route has always been preferred route for formulators and has dominated over other routes of administrations. However this preferred route is limited to those drugs molecule that are permeable across the gastric mucosa and are at least sparingly soluble. Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability.SMEDDS are isotropic mixtures of oil, surfactant, co-surfactant and drug with a unique ability to form fine oil in water microemulsion upon mild agitation following d...