Segrosome
Multiprotein Complex
Herausgegeben: Quincy, Ferdinand M.
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Segrosomes are protein complexes that ensure accurate segregation (partitioning) of plasmids or chromosomes during bacterial cell division. Just as higher forms of life have evolved a complex mitotic apparatus to partition duplicated DNA during cell division, bacteria require a specialized apparatus to partition their duplicated DNA. In bacteria, segrosomes perform the function similar to that performed by mitotic spindle. Therefore, segrosomes can be thought of as minimalist spindles. Segrosomes are usually composed of three basic components- the DNA (plasmid or chromosome) that needs to be s...
Segrosomes are protein complexes that ensure accurate segregation (partitioning) of plasmids or chromosomes during bacterial cell division. Just as higher forms of life have evolved a complex mitotic apparatus to partition duplicated DNA during cell division, bacteria require a specialized apparatus to partition their duplicated DNA. In bacteria, segrosomes perform the function similar to that performed by mitotic spindle. Therefore, segrosomes can be thought of as minimalist spindles. Segrosomes are usually composed of three basic components- the DNA (plasmid or chromosome) that needs to be segregated into daughter cells, a motor protein that provides the necessary physical forces for accomplishing the segregation and a DNA binding protein that connects the DNA and the motor protein, to form the complete segrosome complex.
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