Salvia officinalis L.

Salvia officinalis L.

Diurnal and seasonal variation in chemical composition and biological activities

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This work explores the diurnal and seasonal variation of polyphenols and essential oils of Salvia officinalis. Chromatographic analysis of essential oils extracted from the aerial parts of S. officinalis by hydrodistillation shows that their chemical composition is strongly dependent on the time and season of harvest. The essential oil of sage officinalis is dominated by either -thujone , or camphor depending on the time or season of harvest. Chromatographic analysis of methanolic extracts of sage reveals the predominance of rosmarinic acid whose content depends on the time and season of harve...