Role of mitochondrial functions in drug resistance of tumor cells

Role of mitochondrial functions in drug resistance of tumor cells

Department of Biochemistry, Faculty of Science Alexandria University-Egypt and University of Texas Medical Branch-USA

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The area of cancer research has become a very actively researched field. The different transitions from cell division to apoptosis are recently under extensive investigations. Apoptosis is a generally controlled mechanism of cell death that is essential for the elimination of cells that can no longer replicate or that have potentially mutagenic damage during normal development and for the maintenance of tissue homeostasis. Research in and around apoptosis has increased substantially since the early 1990s. In addition to its importance as a biological phenomenon, defective apoptotic processes h...