Role of Capsule in Pathogenesis of Klebsiella pneumoniae in Rat Model

Role of Capsule in Pathogenesis of Klebsiella pneumoniae in Rat Model

Prevalence of Klebsiella spp. as a Nosocomial Bacteria and Role of Capsule in pathogenesis of K. pneumoniae in Rat model

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This study is designed to compare total polysaccharide concentrations extracted from isolated Klebsiella pneumoniae,and to investigate the cellular events leading to pneumonia by K. pneumoniae with highest capsular polysaccharide and contributions each of CP & lipopolysaccharide (LPS) in this process.For determination amount of CP in all isolates,total polysaccharide was extracted by heating method their quantification was done on the bases of standard glucose curve.Obtained results were revealed that K. pneumoniae differ in their CP concentrations in regard to the site of isolation.The highes...