Ribozymes and RNA Catalysis
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The emphasis of this book concerns the origins of catalysis in RNA. This necessarily includes a significant discussion of structure and folding, with the main thrust of the book being chemical mechanism. Despite the importance of RNA catalysis in the cell, its origins are still poorly understood and often controversial. RNA catalysis is important in many aspects of cell function, including RNA processing and translation. Ribozymes may hold the key to the origins of life on this planet, and can still teach us a lot about biocatalytic mechanisms in general. There has been a significant coming to...
The emphasis of this book concerns the origins of catalysis in RNA. This necessarily includes a significant discussion of structure and folding, with the main thrust of the book being chemical mechanism. Despite the importance of RNA catalysis in the cell, its origins are still poorly understood and often controversial. RNA catalysis is important in many aspects of cell function, including RNA processing and translation. Ribozymes may hold the key to the origins of life on this planet, and can still teach us a lot about biocatalytic mechanisms in general. There has been a significant coming together in the field in recent years and this book offers a good review of the whole field.
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