Review: Synthetic methods and anti-microbial importance of thiazole

Review: Synthetic methods and anti-microbial importance of thiazole

Thiazole synthesis and Anti-microbial study

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Data on the synthesis of thiazoles systems from thioamide, thiourea, thiosemicarbazide, and labile sulfur was reviewed. The principal directions in the practical application of these substances are briefly discussed. Thiazole derivatives are important class of sulfur containing heterocyclic compounds, found in many potent biologically active molecules such as Cefdinir (antibacterial drug, semisynthetic third generation cephalosporin drug), flucloxacillin (androgenic steroid danazol), Pramipexole (The dopamine D2-agonist), Sulfathiazol (antimicrobial drug), Ritonavir (The HIV-1 protease inhibit...