Regulatory Autoantibodies Targeting G-Protein-Coupled Receptors
Broschiertes Buch

Regulatory Autoantibodies Targeting G-Protein-Coupled Receptors

Book of Abstracts 2018 - Advances in Regulatory Autoantibody Research

Herausgeber: Riemekasten, Gabriela; Kerstein, Anja
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This book concludes the results of the 2nd symposium on functional or regulatory autoantibodies targeting G-protein-coupled receptors (GPCRs) in Lübeck in 2018. GPCRs are involved in a variety of physiological and pathophysiological processes. So far, much effort has been made on anti-GPCR drug discovery with a focus on the development of small molecules for the treatment of cancer, infection, metabolic disorders or inflammatory diseases. Recently, functional autoantibodies against GPCRs were identified in healthy donors and were found to be dysregulated in various diseases. They are associat...