Recent Progress in Toxicity and Drug Testing
Gebundenes Buch

Recent Progress in Toxicity and Drug Testing

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Present-day drug design and testing includes experimental in-vitro and in-vivo measurements of the drug candidate's adsorption, distribution, metabolism, elimination and toxicity (ADMET) properties in the initial stages of drug discovery. Just a poor percentage of the recommended drug candidates get the authorization of government and reach the market place. Disadvantageous pharmacokinetic properties, bad bioavailability and efficiency, negative side effects, poor solubility and toxicity matters are responsible for most of the drug failures confronted in the pharmaceutical industry. Authors fr...