Recent Progress in Synthesis/Uses of Aminophosphonic Acids Analogues
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Phosphonates, as we have shown in this book, phosphonate reagents and their diverse reactivity are very useful in the synthesis of biologically active products. Their use as substrates and key intermediates allows the synthesis of very complex structures to be carried out. The phosphonate-based methods compare favorably in terms of brevity (shortens) and use of simple reagents with the majority of the previously reported syntheses. Another advantage of the use of phosphonates is that the presence of phosphorus in starting materials and intermediates allows the course of each synthetic step to ...
Phosphonates, as we have shown in this book, phosphonate reagents and their diverse reactivity are very useful in the synthesis of biologically active products. Their use as substrates and key intermediates allows the synthesis of very complex structures to be carried out. The phosphonate-based methods compare favorably in terms of brevity (shortens) and use of simple reagents with the majority of the previously reported syntheses. Another advantage of the use of phosphonates is that the presence of phosphorus in starting materials and intermediates allows the course of each synthetic step to be followed by means of 31P-NMR spectroscopy. While this review presents a small sample of the uses of phosphonates in synthesis, they have been and will continue to be important reagents for synthetic chemists in the future.
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