Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole
Gebundenes Buch

Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole

Type Compounds I

Herausgeber: Silva, Vera L. M.; Silva, Artur M. S
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Pyrazoles and their reduced form, pyrazolines, are considered privileged scaffolds in medicinal chemistry, owing to their noteworthy biological activities, physicochemical properties and occurrence in many low-molecular-weight compounds present in several marketed drugs (e.g., Celebrex® and Viagra®). Pyrazoles are also found in a variety of agrochemicals (fungicides, insecticides, and herbicides) and are versatile compounds for synthetic manipulations. Their challenging chemical structures and properties (mainly tautomerism, with possible implications in their reactivity), and diverse applic...