Protein Tyrosine Kinases

From Inhibitors to Useful Drugs

Herausgegeben: Fabbro, Doriano; McCormick, Frank
Versandkostenfrei!
Versandfertig in über 4 Wochen
208,99 €
inkl. MwSt.
PAYBACK Punkte
104 °P sammeln!
Leading researchers, from the Novartis group that pioneered Gleevec/Glivec(TM) and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases, including cancer. Highlights include a discussion of the rationale and the progress made towards generating "selective" low molecular-weight kinase inhibitors; an analysis of the normal function, role in disease, and application of platelet-derived growth fa...