Broschiertes Buch

Protein Quality Control in Neurodegenerative Diseases

Beschreibung

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

Produktdetails

• Research and Perspectives in Alzheimer's Disease
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-642-44706-8
• 2013
• Seitenzahl: 148
• Erscheinungstermin: 29. Januar 2015
• Englisch
• Abmessung: 235mm x 155mm x 9mm
• Gewicht: 237g
• ISBN-13: 9783642447068
• ISBN-10: 3642447066
• Artikelnr.: 42960973

Rezensionen

From the reviews:
"This is a very good cutting edge book of scholarly import on the functioning of molecules and signal transduction in both neurodegeneration and neuroprotection. ... I recommend this book highly to scientists in disease pathophysiology work." (Joseph J. Grenier, Amazon.com, June, 2014)