Preparation & Evaluation of Fexofenadine HCL Lozenges by Jaggery

Preparation & Evaluation of Fexofenadine HCL Lozenges by Jaggery

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The aim of the present study was to develop lozenges of Fexofenadine hydrochloride by using Jaggery as sweetener. Fexofenadine hydrochloride is an antihistamine with selective peripheral H1-receptor antagonist activity. It is used in the treatment of hay fever and similar allergy symptoms. Fexofenadine hydrochloride is a poor water-soluble drug with a bitter taste. Because of sore throat conditions, patients may experience difficulty in swallowing a tablet. Therefore, lozenge would serve as an ideal dosage form for patients which require quick relief. In order to assist patients during traveli...