Predicting the Lineage Choice of Hematopoietic Stem Cells
Manuel Kroiss
Broschiertes Buch

Predicting the Lineage Choice of Hematopoietic Stem Cells

A Novel Approach Using Deep Neural Networks

Versandkostenfrei!
Versandfertig in 6-10 Tagen
38,99 €
inkl. MwSt.
Weitere Ausgaben:
PAYBACK Punkte
19 °P sammeln!
Manuel Kroiss examines the differentiation of hematopoietic stem cells using machine learning methods. This work is based on experiments focusing on the lineage choice of CMPs, the progenitors of HSCs, which either become MEP or GMP cells. The author presents a novel approach to distinguish MEP from GMP cells using machine learning on morphology features extracted from bright field images. He tests the performance of different models and focuses on Recurrent Neural Networks with the latest advances from the field of deep learning. Two different improvements to recurrent networks were tested: L...