Plasma free amino acids changes in HCC patients
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The aim of the book is to investigate plasma free amino acids profile as a possible diagnostic/prognostic factor in hepatocellular carcinoma patients. This study included 71 Hepatocellular cacinoma patients, and 30 chronic HCV patients in addition to 30 healthy controls. Laboratory investigations including; complete blood picture, liver function tests, serum alpha fetoprotein, hepatitis viral markers. The book showed a statistically significant increase of methionine, tyrosine, ornithine, citrulline, glycine, phenylalanine, alanine, glutamate, proline, and arginine and decrease of valine, aspa...
The aim of the book is to investigate plasma free amino acids profile as a possible diagnostic/prognostic factor in hepatocellular carcinoma patients. This study included 71 Hepatocellular cacinoma patients, and 30 chronic HCV patients in addition to 30 healthy controls. Laboratory investigations including; complete blood picture, liver function tests, serum alpha fetoprotein, hepatitis viral markers. The book showed a statistically significant increase of methionine, tyrosine, ornithine, citrulline, glycine, phenylalanine, alanine, glutamate, proline, and arginine and decrease of valine, aspartate, leucine/isoleucine, BTR and fischer ratio in hepatocellular carcinoma compared to control group. Also, it indicated that there was a statistically significant correlation between BTR and platelets, alanine transaminase, albumin, bilirubin and alpha fetoprotein and significant differences in BTR among Child-Pugh A, B and C. Our results suggested that the plasma free amino acids profileis considered valuable for diagnosis and nutritional care in cancer patients.Furthermore, BTR reflects the pathological liver background with a high degree of correlation to other liver functional markers.
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