Plasma Elemental Concentrations, Auditory Pathway Disorder, and Auditory Deficits in OSMF
Auriga
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Plasma Elemental Concentrations, Auditory Pathway Disorder, and Auditory Deficits in OSMF

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The pathogenesis of OSMF has multifactorial etiology including nutritional deficiencies, ingestion of chillies, habit of chewing areca nut, factors like pollution and genetic and immunologic processes. 1. Chewing of Areca nut (betel nut): The major component of betel quid is areca nut, tobacco, lime and piper leaf. Betel nut is a major etiologic agent in OSMF. Betel nut consists of arecoline, an active alkaloid which stimulates fibroblast to increase production of collagen by 150%and also upregulates COX-2 expression. It causes increased collagen production leading to fibrosis. Areca nut quid ...